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"Microfluidics-Enabled Multimaterial Maskless Stereolithographic Bioprinting" (2018,30, 1800242)

dc.contributor.authorMiri, Amir K.
dc.contributor.authorNieto, Daniel
dc.contributor.authorPalmero Iglesias, Luis Manuel
dc.contributor.authorHosseinabadi, Hossein Goodarzi
dc.contributor.authorMaharjan, Sushila
dc.contributor.authorRuiz Esparza, Guillermo U.
dc.contributor.authorKhoshakhlagh, Parastoo
dc.contributor.authorManbachi, Amir
dc.contributor.authorDokmeci, Mehmet Remzi
dc.contributor.authorChen, Shaochen
dc.contributor.authorShin, Su Ryon
dc.contributor.authorZhang, Yu Shrike
dc.contributor.authorKhademhosseini, Ali
dc.date.accessioned2026-07-01T07:48:12Z
dc.date.available2026-07-01T07:48:12Z
dc.date.issued2025
dc.identifier.citationMiri, A. K., Nieto, D., Palmero Iglesias, L. M., Hosseinabadi, H. G., Maharjan, S., Ruiz Esparza, G. U., Khoshakhlagh, P., Manbachi, A., Dokmeci, M. R., Chen, S., Shin, S. R., Zhang, Y. S., y Khademhosseini, A. (2025). "Microfluidics-Enabled Multimaterial Maskless Stereolithographic Bioprinting" (2018,30, 1800242). Advanced Materials, 37(41). https://doi.org/10.1002/adma.202512660es
dc.identifier.issn0935-9648, 1521-4095
dc.identifier.urihttp://hdl.handle.net/20.500.12251/4271
dc.description.abstractA stereolithography-based bioprinting platform for multimaterial fabrication of heterogeneous hydrogel constructs is presented. Dynamic patterning by a digital micromirror device, synchronized by a moving stage and a microfluidic device containing four on/off pneumatic valves, is used to create 3D constructs. The novel microfluidic device is capable of fast switching between different (cell-loaded) hydrogel bioinks, to achieve layer-by-layer multimaterial bioprinting. Compared to conventional stereolithography-based bioprinters, the system provides the unique advantage of multimaterial fabrication capability at high spatial resolution. To demonstrate the multimaterial capacity of this system, a variety of hydrogel constructs are generated, including those based on poly(ethylene glycol) diacrylate (PEGDA) and gelatin methacryloyl (GelMA). The biocompatibility of this system is validated by introducing cell-laden GelMA into the microfluidic device and fabricating cellularized constructs. A pattern of a PEGDA frame and three different concentrations of GelMA, loaded with vascular endothelial growth factor, are further assessed for its neovascularization potential in a rat model. The proposed system provides a robust platform for bioprinting of high-fidelity multimaterial microstructures on demand for applications in tissue engineering, regenerative medicine, and biosensing, which are otherwise not readily achievable at high speed with conventional stereolithographic biofabrication platforms.es
dc.language.isoenges
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.title"Microfluidics-Enabled Multimaterial Maskless Stereolithographic Bioprinting" (2018,30, 1800242)es
dc.typearticle
dc.identifier.doi10.1002/adma.202512660
dc.identifier.urlhttps://www.webofscience.com/wos/woscc/full-record/WOS:001531397600001
dc.issue.number41es
dc.journal.titleAdvanced Materialses
dc.rights.accessRightsopenAccesses
dc.subject.keywordEconomía circulares
dc.subject.keywordAcústicaes
dc.subject.keywordAccesibilidad universales
dc.subject.keywordPlanificación urbanísticaes
dc.subject.keywordCalidad urbanaes
dc.subject.keywordEdificios saludableses
dc.subject.unesco1203.17 Informáticaes
dc.subject.unesco3305.37 Planificación Urbanaes
dc.subject.unesco3312 Tecnología de Materialeses
dc.subject.unesco2201.02 Acústica Arquitectónicaes
dc.subject.unesco6310.09 Calidad de Vidaes
dc.subject.unesco3212 Salud Publicaes
dc.volume.number37


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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